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Lead and its inorganic compounds are neurotoxins which may produce peripheral neuropathy. For an overview of the effects of lead exposure, consult Occupational Safety and Health Administration Appendix A of Occupational Exposure to Lead (29CRF1910. 1025) Tin and its organic compounds are primary chemical irritants of the skin, and stannic oxide has been shown to cause benign pneumoconiosis. Calcium and strontium compounds should be considered toxic only when theycontain toxic substances.